Affleck and the "Get Right" singer boarded a private plane in Los Angeles just days before his 50th birthday.
They are joined by the actor's children Violet, 16, Seraphina, 13, and Samuel, 10, whom he shares with Jennifer Garner, on the milestone day.
Lopez wore a white button-down and flare-leg jeans for the flight. A Swarovski-encrusted bling cup and black aviator sunglasses complemented her honey-blonde hair.
During the trip, the Justice League actor wore a black jacket, a white t-shirt, and black jeans, along with aviators.
Lopez and her husband spent their honeymoon and family vacation in Paris to celebrate Lopez's birthday. According to an insider, the newlyweds are "unbelievably happy" after their Paris honeymoon.
Mrs. Affleck stated that she feels "amazing and happier than ever." She also discussed what makes her feel beautiful, including her husband's admiration of her natural beauty.
He says, "I like you when you don't have anything on.". No hair, no makeup, just you. That means a lot to him. That makes me feel really confident and beautiful.
You can see the essence of who you are and your skin, and he appreciates that I take care of that. "That makes me feel really beautiful as well."